Establishment of a lymphoblastoid cell line and isolation of an Epstein-Barr-related virus of gorilla origin.

نویسندگان

  • R H Neubauer
  • H Rabin
  • B C Strnad
  • M Nonoyama
  • W A Nelson-Rees
چکیده

A B-lymphoid cell line was established from a normal gorilla. The cells contained Epstein-Barr virus-related antigens, and herpesvirus particles were demonstrated by electron microscopy. DNA-DNA reassociation kinétics revealed 30 to 40% hybridization to Epstein-Barr virus with 50 genomes per cell. Examination of the viral nuclear antigen with gorilla sera showed this to be a unique isolate termed Herpesvirus gorilla. H. gorilla transformed gibbon B-lymphocytes in vitro.

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عنوان ژورنال:
  • Journal of virology

دوره 31 3  شماره 

صفحات  -

تاریخ انتشار 1979